Azepane

• Hexamethylenimine
• Hexahydroazepine
• Azacycloheptane
• Homopiperidine

Colorless liquid with an ammoniacal odor

Liquid

0.86 g · cm -3

-37 ° C

135-138 ° C

12.5 hPa ( 20 ° C)

Miscible with water

1.4631 (20 ° C)

Risk

20.7 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Azepan is a saturated heterocyclic chemical compound. It is the easiest seven-membered nitrogen-containing heterocycle, and is also often referred to as hexamethylenimine. This term is misleading, because it is not an imine in the true sense. Another name is homopiperidine, since it is a homolog of the piperidine, which is expanded by a methyl group is.

Production

The synthesis of azepan can be carried out by reduction of ε -caprolactam with lithium aluminum hydride or sodium borohydride. The cyclization of 1,6- diaminohexane, for example, the ruthenium catalyst (in this case tris ( triphenylphosphine ) dichlororuthenat (II) ) represents a synthesis

Properties

Azepan is a colorless liquid with an ammoniacal odor. It is completely miscible with water. It is a nitrogen base. Your pKa in water at 20 ° C 11.4.