Basophilia

As basophilia an increase in the number of basophils is (in short: basophils ) referred to in the blood. Which is a form of basophilic leukocytosis, thus increasing the number of white blood cells. Furthermore, called basophilia and the coloring property of cells, respectively, cell organelles in cyto - and histological examinations, a property, which derive their name from the basophil. As basophilic (mostly) acid molecule groups are referred to in the tissue, which can be good with basic dyes (eg blue with hematoxylin in the hematoxylin -eosin stain ) stain. See in particular under histology ( histology staining methods section ).

Basophilia in hematology

Basophils are produced in the bone marrow and have the same precursor cell as mast cells. They circulate in the blood for only a few minutes and then migrate into tissues, where they remain for several weeks.

Basophilia is often associated with eosinophilia. Causes of basophilia are allergies and hypersensitivity reactions. In addition, it is common in parasites to a basophilia ( heartworm disease, other diseases caused by nematodes infestation with ticks or flea allergies). A hyperlipoproteinemia, ie a metabolic or endocrine disorder with an increase in blood lipids, may also be connected to a basophilia. The basophilic leukemia is a very rare tumor. In chronic myelogenous leukemia, there is also an increase in Basophilenzahl.

Basopenie

The Basopenie is a decrease of basophils in the blood. It is difficult to prove because the Basophilenzahl is already physiologically relatively small. The cause either endogenously related ( stress) or by administering a drug are mainly elevated glucocorticoid levels in question.