Bcl-2-associated death promoter
- OMIM: 603 167
- MGI: 1096330
Bcl- 2- antagonist of cell death (BAD) is a pro-apoptotic protein of the Bcl- 2 family.
Its effect, it develops, characterized in that it binds an apoptosis -inhibiting protein, and deactivated. If BAD is phosphorylated by the protein kinase B ( by PI 3-kinase in a signal initiated ), it can no longer bind the apoptosis -inhibiting protein.