Canine parvovirus (CPV -2) is a virus which causes the parvovirus in dogs. The CPV is a non-enveloped DNA virus of approximately 18 to 26 nanometers in diameter.
1978, was first isolated from dogs with high acute infections and called virus type 2 (CPV -2). This name comes from the fact as the pathogen for the first time in 1968 as Minute Virus of Canines (MCV ) was described incorrectly referred to as CPV -1. The MCV only occurred in dogs with mild diarrhea, its pathogenicity is controversial.
Probably skipped the CPV -2, the species barrier and emerged - as the virus of infectious panleukopenia the mustelids - by mutation from the feline parvovirus ( FPV), the trigger of feline distemper. The encrypted in FPV genetic information agree to 99% with those of CPV-2 match.
Mutations of the CPV-2, which are characterized by changes in the amino acid sequence in the so-called VP2 protein were observed soon after the occurrence. These so-called CPV -2a and -2b types spread rapidly around the world. CPV -2a and -2b are for domestic cats also again infectious, although the disease usually runs here subclinical. Of 2000, in Italy for the first time, a further mutant (CPV - 2c), which has now spread all over Europe and South America.
Literature and sources
Katrin Hartmann and Peter F. Suter: viral infections. In: Peter F. Suter and Hans G. Nobody ( Ed.): Practical dog clinic. Paul Parey Verlag, 10th Edition 2006, pp. 276-290, ISBN 3-8304-4141- X
- Virus species