Carbendazim

• Methylbenzimidazole -2- ylcarbamate
• N-( benzimidazol-2- yl) carbamic acid methyl ester
• 2 - ( methoxycarbonylamino )-benzimidazole
• BMC
• Carbendazol
• Derosal
• Bavistin

Colorless and odorless solid

Fixed

1.5 g · cm -3

302-307 ° C ( decomposition)

0.09 MPa ( 25 ° C)

• Insoluble in water (8 mg · l-1 at 24 ° C)
• Sparingly soluble in ethanol ( 300 mg · l-1 at 20 ° C)
• Slightly soluble in dimethylformamide (5 gl -1 at 20 ° C)

Risk

• 6400 mg · kg -1 ( LD50, rat, oral)
• 8500 mg · kg -1 ( LD50, Rabbit, transdermal)

Template: Infobox chemical / molecular formula search available

Carbendazim is a world frequently used pesticide ( fungicide) from the group of benzimidazole carbamates, which is used against fungal infestation in a number of fruits, fruit and vegetables. In Germany and Austria it is used mainly in grain cultivation, in Switzerland it is approved against various fungal diseases in fruit, vegetables and ornamental plants. In addition, it is used in silicone sealants as fungal inhibitors.

Production and representation

Carbendazim can be obtained by a multistep reaction. First thiourea and dimethyl sulfate can be reacted, which subsequently react with sodium hydroxide in the presence of methyl chloroformate. The product reacted with o- phenylenediamine and formic acid to carbendazim and methanethiol.

Properties

Carbendazim is a colorless, odorless, practically insoluble in water solid. It has no anticholinesterase activity and is produced commercially since the 1970s. It also occurs as a metabolite of other benzimidazole fungicides.

Safety

Carbendazim is classified as germ cell mutagen category 1B ( according to the CLP Regulation ), so one of the substances for which there is impairment of germ cells has been demonstrated in animal experiments.