Carter Manasco attended a public school and the Howard College in Birmingham ( Alabama). He graduated in 1927 at the Law Faculty of the University of Alabama in Tuscaloosa with a Bachelor of Laws degree in 1929 with a Juris Doctor. He was admitted as a lawyer in the same year and then started in Jasper (Alabama ) to practice.
Manasco also pursued a political career. He was 1930-1934 Member of the House of Representatives from Alabama. During this time he was secretary of the 1933 Speakers William B. Bankhead, a post he held until 1940. Manasco was elected to the 77th Congress, there to fill the vacancy that was created by the resignation of Walter W. Bankhead. He was reelected to the three succeeding U.S. Congresses, but suffered in his candidacy in 1948 in the 81st U.S. Congress defeat. Manasco worked in the U.S. House of Representatives on June 24, 1941 to January 3, 1949. During this time, he had presided over the Committee on Expenditures in Executive Departments ( 78th and 79th U.S. Congress ).
After the end of his tenure, he went back to his work as a lawyer after, but also dealt with public relations ( PR ). He was 1947-1949 a member of the first Hoover Commission on Reorganization of the Executive Departments. He then worked 1949-1985 as a legal consultant (legislative counsel ) for the National Coal Association. Manasco lived in McLean (Virginia ), where he died in 1992. He was buried at Arlington National Cemetery.