Casal Cermelli ( Piedmontese Casal SIRME or Casassirmé ) is a municipality with 1210 (as of 31 December 2012) a population of Alessandria in the Italian province (AL ), Region Piedmont.
The municipality consists of the villages of Fanta aces, Portanova and Rossina. The neighboring municipalities are Bosco Marengo, Castellazzo Bormida, Frugarolo and Predosa. The patron saint of the town is Santa Maria Assunta.
The village lies at an altitude of 102 m above sea level. The municipality covers an area of 11.64 km ².