Ceftaroline fosamil

  • (6R,7R)-7-{[(2Z)-(Ethoxyimino)[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino}-3-[4-(1-methylpyridinium-4-yl)thiazol-2-yl]sulfanyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylat
  • TAK -599
  • 229016-73-3 ( Ceftarolinfosamil )
  • 595568-96-0 ( Ceftarolinfosamilacetat )

Antibiotic

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Ceftarolinfosamil is a drug with antibiotic action.

It is the N -phosphono prodrug of Ceftarolin, a cephalosporin antibiotic with high effectiveness against methicillin-resistant staphylococci ( MRSA) and other multidrug-resistant problem bacteria (VISA, VRSA, PRSP), as well as against gram -negative bacteria, but not against ESBL -producing Enterobacteriaceae, and non- fermentor.

It was developed approved by the Japanese pharmaceutical company Takeda and in October 2010 by the FDA for the treatment of adults with community-acquired pneumonia and acute skin and soft tissue infections.

CAS registry number PubChem
171596
de