Centromere

As a centromere or centromere ( Kentron of Greek κέντρον, focus ' and μέρος Meros, part ' ) refers to the range of the primary constriction ( constriction ) of a metaphase chromosome. Here hang the two chromatids together until they are separated during the nuclear division (mitosis or second meiotic division ) at the onset of anaphase: On the located at the centromere -forming protein complexes, kinetochores, put on the fibers of the spindle apparatus, the sister chromatids to opposite pull cell poles. The centromere divides each chromatid in two arms, the length of which often differs significantly.

Likewise, the cohesin is ( the protein that holds the chromosome ) never removed until the prophase of mitosis in the centromeric region of the chromatid chromosomes.