Chenodeoxycholic acid

  • 3α, 7α - dihydroxycholanic acid
  • (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentansäure (IUPAC)

A05AA01

White crystalline powder

165-167 ° C

4000 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Chenodeoxycholic acid, cholic acid belongs next to the primary bile acids. Chemically it is the group of sterols ( sterols ) belonging steroid. Its salts are called Chenodesoxycholate.

Biochemistry

Education

Chenodeoxycholic acid is one of the four most commonly produced by the liver acids. It is made there over the intermediate pregnenolone from cholesterol.

Function

Chenodeoxycholic acid and other bile acids that act as an emulsifier. During digestion they emulsify fats, making them so accessible to lipases.

Approximately 90 % of the bile acids are reabsorbed in the small intestine and thus reach for reuse back into the liver back.

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Dangerous Substances Directive (67/548/EEC)
181118
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