Hynde worked in the early 1970s as a composer in the United States and France. They did not manage to get a record deal. In 1973 the former art student first time to London. There they sold leather bags in Oxford Street and stood at the " Central Saint Martins College of Art and Design" model. For a short time she wrote for the New Musical Express article. Then she worked in the clothes shop Malcolm McLaren. In late 1973 they played in Paris at the Frenchies before they briefly returned to Akron in 1975. There they joined the rhythm-and - blues band Jack Rabbit.
1976 Hynde returned back to London. There they founded the Berk Brothers, which it parted again soon. She also worked as a studio musician for Chris Spedding, Johnny Thunders and Mick Farren. An offer from Nick Lowe to join his band, they refused. In August 1977 she took with The Phone Call on a first demo tape.
In 1978, Hynde the Pretenders, whose success was not long in coming. Hynde was a singer, guitarist and composer of the band. Following the release of their debut album, Hynde met Ray Davies in 1980 in New York know. In February 1983, their daughter Natalie was born. In 1984, Hynde separated by Davies and married on 5 May of the same year Jim Kerr, the lead singer of Simple Minds. In April 1985, the daughter Yasmin Paris was born. In the same year Hynde recorded a cover version of Sonny and Cher classic I Got You Babe with UB40.
In 1988, Hynde played with UB40 on the celebration of the seventieth birthday of Nelson Mandela the song Breakfast in Bed, who also appeared as a single. In 1989, Hynde with the law in conflict. On June 8, she had announced at a press conference held by Greenpeace to try to throw a fire bomb in a McDonald's restaurant. The following day, a McDonald's restaurant was actually destroyed in Milton Keynes by an incendiary device. After a judicial process, Hynde undertook to refrain from making such statements in the future. End of 1989, Hynde separated by Kerr and engaged for the Animal Rights movement. In 1997, the vegetarian and active environmentalist married the artist Lucha Brieva.
In 2009, Chrissie Hynde participated in the Christmas single Postcard From London the former Kinks frontman Ray Davies before under the name of JP, Chrissie & the Fairground Boys called 2010 a new project to life and an album called Fidelity! published. In the same year, Hynde has with other musicians (David Gilmour, Bob Geldof and Gary McKinnon itself) the rock classic Chicago by Crosby, Stills, Nash & Young re-recorded with the consent of composer Graham Nash, to protest against the extradition of Gary McKinnon to the United States to protest and to support this with a simultaneous call for donations.