Christie Ann Hefner studied English and American literature at Brandeis University. She joined the company in 1977, her father, and in 1988 finally chairman of the board. Under her leadership, the company completed the development of the new media, especially through websites such as Adult.com.
Hefner made in the United States as a philanthropist a name. They supported, for example, with 30 million U.S. $ a foundation for HIV sufferers. In the Forbes list of the most influential women Hefner came in 2005, 2006 and 2007 in the top 100, they still engaged in the think tank Center for American Progress.
In December 2008 Hefner announced her resignation from the Board on 31 January 2009.