Chromosomal inversion

As inversion (from the Latin inversio, the inversion) is referred to in genetics a certain change of a chromosome: A chromosomal segment is rotated by 180 °, ie "inverted". Inversions are held by a chromosome breaks in two places ( DNA double -strand break ) and is re-assembled, the section between the two break points but is installed in reverse order. Characterized the sequence of the genes on this chromosome portion is reversed. Inversions are among the chromosome mutations

One distinguishes between pericentric inversion, in which the reverse portion includes centromere and paracentric inversion, for which this is not the case. Inversions may occur by the so-called balancer chromosomes, in which the recombination is suppressed.

Source

  • R. Wehner, W. Gehring: Zoology, 23 revised edition; Georg- Thieme- Verlag, Stuttgart, New York 1995, ISBN 3-13-367423-4
  • Genetics
  • Cell Biology
  • Mutation
Chromosome abnormality
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