Dalrymple's sign

The Dalrymple mark is a Lidveränderung in thyroid eye disease. It is named after the British ophthalmologist John Dalrymple ( 1803-1852 ).

The endocrine ophthalmopathy is next to the part of the disease hyperthyroidism in Graves' disease, very rarely in chronic Immunthyreopathie ( Hashimoto 's thyroiditis ). This leads the eye to the inflammatory infiltration of the adipose tissue of the eye socket (orbit ), the muscles of the eye and eyelids, and subsequently to a massive swelling, whereby the eyeball from the orbit is pushed out ( exophthalmos ).

The Dalrymple sign here describes the fact that the white sclera ( limbus corneae ) because of an excessively enlarged palpebral fissure and over the edge of the cornea is visible. Different characteristics can be measured and press the distance between the limbus and lid margin in mm.

Other clinical signs and Lidveränderungen in Graves' ophthalmopathy are the Graefe sign, the Gifford- character Stellwag character that kettle characters and the Möbius characters.