Deoxycytidine

  • DC, CdR or dCyd ( short code )
  • 2'- deoxycytidine
  • 1- β -D - Desoxyribofuranosylcytosin
  • 1 - [( 2R, 4S, 5R )-4- hydroxy-5- (hydroxymethyl) oxolane -2-yl ] -4-amino -pyrimidin- 2-one

Colorless to pale yellow crystalline powder

Fixed

209-211 ° C

50 mg / ml of water

Template: Infobox chemical / molecular formula search available

Deoxycytidine ( dC or short DNA sequences only C) is a nucleoside and consists of the nucleobase cytosine, and the β -D -deoxyribose sugar.

Deoxycytidine is part of the deoxyribonucleic acid ( DNA), where it forms a base pair with deoxyguanosine. The analogue with ribose is the cytidine.

Depending on the number of phosphate residues, it forms the basis for the nucleotides Desoxycytidinmonophosphat ( dCMP ), Desoxycytidindiphosphat ( dCDP ) or deoxycytidine triphosphate ( dCTP ).

Under physiological conditions, a small fraction of deaminated deoxycytidine contained in the DNA at deoxyuridine, for which special repair systems exist in cells. In the deamination of 5 - methyldeoxycytidine but the deoxythymidine also normally contained in the DNA, which can not be detected as faulty, which can mate in the next round of replication with deoxyadenosine, which then yields a transition from deoxycytidine by deoxythymidine and on the created opposite DNA strand will yield of deoxyguanosine by deoxyadenosine.

Derivatives

CAS registry number PubChem
258304
de