Dimethoxyethane

Colorless liquid with ethereal odor

Liquid

0.87 g · cm -3 ( 20 ° C)

-58 ° C

84 ° C.

78 hPa ( 20 ° C)

Miscible with water

1.3770 (25 ° C)

Risk

Template: Infobox chemical / molecular formula search available

Ethylene glycol dimethyl ether also known as 1,2-dimethoxyethane, DME, glyme, monoglyme, Dimethylglycol, dimethyl cellosolve, is a clear, colorless, completely water-miscible liquid which is used as aprotic solvent. It is often used as a substitute for high-boiling diethyl ether or THF, for example in organometallic chemistry ( Grignard reaction ) and for palladium-catalyzed reactions (Suzuki, Stille coupling).

Properties

Ethylene glycol dimethyl ether-like odor and has a may form explosive peroxides on standing in air when exposed to light. It is very flammable and forms with air from 1.6 to 10.4 % by volume of explosive mixtures.

DME is an excellent solvent which is miscible with both water almost indefinitely, as well as with many organic compounds. Thus, it is for example possible to react salts with organic compounds. Also oligo-and polysaccharides may be used.

Safety

1,2- dimethoxyethane is dangerous to health when inhaled and may result in higher concentrations for anesthesia. It can also damage the reproductive ability and the child in the womb. Alcohol the mother potentiates the effects on fertility.