Dimethylethanolamine

  • Dimethyl
  • 2 - ( dimethylamino) ethanol
  • N, N -dimethylethanolamine
  • Norcholin
  • DMAE
  • Deanol

Colorless liquid with an ammoniacal odor

Nootropics

Liquid

0.89 g · cm -3 ( 20 ° C)

-40 ° C

131 ° C.

5.6 hPa ( 20 ° C)

Miscible with water, ethanol,

1.4300 (20 ° C)

Risk

Template: Infobox chemical / molecular formula search available

Dimethylaminoethanol ( DMAE) is a monohydric primary alcohol, which still carries a dimethylamino group. It's about the choline ( the Trimethylethanolammonium cation ) are closely related to the neurotransmitter acetylcholine. DMAE is a colorless to yellowish liquid of an amine-like odor. Aqueous solutions are basic.

Occurrence

As a metabolic product of the metabolism of choline dimethylaminoethanol occurs in many living things. Larger quantities can be found in fish ( sardines, salmon, anchovies ).

Production and representation

Dimethylaminoethanol can be synthesized by methylation of monoethanolamine. Technically, it is obtained by reacting dimethylamine with ethylene oxide ( BASF process ).

Use

Dimethylaminoethanol place as a means for dispersing pigments in water-based paints use. Furthermore, it is required as an intermediate or starting material for the preparation of dyestuffs, emulsifiers, corrosion inhibitors, textile auxiliaries, cosmetics and pharmaceuticals.

The dimethylaminoethanol are a number of positive effects, so among other nootropic effects have been alleged, but for which clear evidence is lacking. In Alzheimer's patients, no consistent results were observed.

Dimethylaminoethanol as a topical gel designed to reduce the formation of wrinkles.

Safety

As the tertiary amine dimethylaminoethanol is a strong base on which the caustic effect is based. It is only low acute toxicity (LD50 (rat, oral): 2.00 g / kg LD50 (rabbit, dermal): 1.37 g / kg).

CAS registry number Vapor pressure Dangerous Substances Directive (67/548/EEC) CRC Handbook of Chemistry and Physics
224385
de