He played between 1945 and 1949 in the college football field for the team from Southern Methodist University and received during his college career in 1947 Maxwell Award and a year later the Heisman Trophy for the best player. The NFL Draft 1949 he was engaged by the Detroit Lions, where he was active from 1950 to 1955. He was elected in 1950 to the NFL Rookie of the Year Award and won with the Detroit Lions in 1952 and 1953, the championship of the National Football League ( NFL). In the years 1950, 1951, 1953, 1954 and 1955 he took part in the Pro Bowl five times, the All-Star game in the NFL.
Doak Walker was inducted into the College Football Hall of Fame in 1986 and into the Pro Football Hall of Fame in 1959. His jersey number 37 is no longer awarded at the Detroit Lions. Named after him since 1990, awarded for the best running back in college area Doak Walker Award. He was married twice, his second wife, the skier Werner Gladys, and father of four children. In September 1998, he died following a skiing accident, he had suffered in January of the same year.