Enteropeptidase

  • OMIM: 606 635
  • UniProt: P98073
  • MGI: 1197523

Enteropeptidase or (deprecated) enterokinase, an enzyme in the brush border of vertebrates, which is formed from the duodenal mucosa. Elimination of a hexapeptide ( Val- [ Asp ] 4- Lys) converts the inactive proenzyme trypsinogen into its active form trypsin, the membrane-bound enteropeptidase, thereby indirectly activates other enzymes of the pancreatic secretion.

The enteropeptidase catalyzes the following reaction:

Swell

  • Roche Lexicon of Medicine, 5th Edition ( http://www.tk-online.de/rochelexikon/ )
  • Robert F. Schmidt, Florian Lang: human physiology with pathophysiology; Springer Medizin Verlag, Heidelberg, 30th edition 2007
  • Peptidase
309372
de