Eric Mabius is Austro- Polish descent with allegedly Irish heritage. After he finished the " Regional High School " in Amherst, Massachusetts, he studied at Sarah Lawrence College in New York, among others Film and acting. This was the starting point for his first smaller Off- Broadway productions and made his first film appearance. He starred in several television series such as Chicago Hope - Final Hope, Party of Five, The OC and The L Word - If women love women. The breakthrough especially among female viewers, however, he succeeded only with the series Ugly Betty, which is similar to the German telenovela Love in Berlin.
His first known films were Cruel Intentions, The Crow III - Deadly Redemption and Resident Evil.
Eric Mabius is married to interior designer Ivy Sherman and has with her two sons.