Eutomer

The eutomer is a term used in medicinal chemistry and refers to the more active in terms of a desired pharmacological effect enantiomer of a chiral drug. In contrast to this relative to the desired pharmacological effect inaktivere enantiomer distomer is called. These designations were introduced as suggested by Everhardus J. Ariens, who also called for the development of enantiomerically pure drugs to reduce drug side effects. Previously, only as racemates ( 1:1 mixture of eutomer and distomer ) used drugs are now often replaced by pure Eutomere. Examples: dexibuprofen, levocetirizine and escitalopram.

The ratio of the potency of the eutomer and distomer of a drug is the ratio eudismische, the decadic logarithm of the eudismische index.