Exfoliatin

Exfoliatine (Latin exfoliation, peeling ) are highly specific bacterial toxins that are produced by certain species and Staphylococcus aureus can cause blistering of the skin in humans and some animals.

A distinction Exfoliatin A ( ETA) and Exfoliatin B (ETB, identical to D), which differ in the mode of inheritance: ETB is plasmid- bound ETA linked trait. The toxic effect is most likely identical. They act as a glutamate- specific serine proteases, which are highly specific cadherin desmoglein I, the columns, granulosum, an adhesion protein in the desmosomes of the stratum granulosum and thus cause intraepidermal cleft between the stratum corneum and the stratum.

In the bloodstream circulating Exfoliatine causing systemic Staphylococcal scalded skin syndrome Hauttoxikose ( SSSS ). In the large- bubble, induced staphylococcal impetigo Exfoliatine are responsible cause of the localized blistering of the skin.

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