Fenoterol

• (RR, SS) - (±) -1 - (3,5- dihydroxyphenyl) - 2 - [ -2 - ( 4-hydroxyphenyl) - 1 - methylethylamino ] ethanol
• (RR, SS) - (±) -1 - (3,5- dihydroxyphenyl) - 2 - [ -2 - ( 4-hydroxyphenyl) - 2 -propylamino ] ethanol

R03AC04, G02CA03

White to off- white crystalline powder (HBr )

β2 -agonists

• Hydrobromide: 222-223 ° C
• Hydrochloride: 182 ° C

Soluble in water and ethanol ( HBr)

Attention

1600 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Fenoterol is a drug from the group of β2 -agonists.

Fenoterol is administered as a spray by inhalation and causes in the lungs by binding as an agonist at the β2 -adrenoceptors of bronchial muscle a widening of the bronchi ( bronchodilation ).

Since it is one of the short-acting bronchodilators, it is used as a rescue medication for asthma or COPD. The effect lasts three to five hours and is a few minutes after inhalation.

Fenoterol acts continue tocolytic, ie an inhibitory effect on uterine contractions. Side effects a reflex tachycardia, a history of angina can be triggered, and the hypoglycemic effect of antidiabetic agents be reduced.

Stereoisomerism

Fenoterol contains two stereocenters. Consequently, there are four stereoisomers. As a drug, the (RR, SS) - racemate is used because it is 9 to 20 times more effective than the (RS, SR ) - enantiomers.