The fine needle biopsy (FNB ), and fine needle aspiration biopsy ( FNAB ) or fine-needle aspiration called, is a process for the recovery of cells from an internal organ or tumors. Microscopic studies should clarify a local cancer suspicion. Examples include fine-needle biopsies of suspicious tumor nodes in salivary gland, thyroid, lung, mediastinum, liver, pancreas and prostate. In lying under the skin suspicious node a short, about 0.75 mm thin needle is inserted under manual control and without local anesthesia. When deeper nodes longer needles are used specifically under ultrasound or x-ray control. By applying suction (negative pressure) with an attached syringe and a fan- shaped movement of the needle, the appropriate amount of a drop of cells is removed by suction, which may comprise thousands of cells from different regions of the fabric. They are applied to glass slides and stained. The assessment is performed by a pathologist.
The fine needle biopsy is in contrast to the punch biopsy is usually painless and causes little complications ( bleeding, infections ). The spread of tumor cells by fine-needle biopsy is only in exceptional cases before .. Upon proof of benign cells can usually a tissue sample by knife or punch biopsy or diagnostic surgery remain. Through further investigations on the cells removed by DNA cytometry, fluorescence in situ hybridization (FISH) or immunocytochemistry allows the diagnostic accuracy of fine-needle biopsy continue to improve.