Fluspirilene

IUPAC: 8 - [4,4 -bis (4 -fluorophenyl) butyl] - 1 -phenyl-1 ,3,8 - triazaspiro [4,5] decan- 4-one

N05AG01

Neuroleptic

188-190 ° C

106 mg · kg -1 ( LD50, mouse, i.m. )

Template: Infobox chemical / molecular formula search available

Fluspirilene is a drug that is used for the treatment of schizophrenia. It is a highly effective antipsychotic drug from the group of Diphenylbutylpiperidine.

The prescription drug is marketed under the brand name Imap ® marketed in Germany ( as an abbreviation for Intramuscular anti - Psychotikum ) and Fluspi ® and fluspirilene beta ®. It ( acute and chronic schizophrenic psychoses productive ( long-term treatment and prevention of relapse ) ) weekly i m in the presence of the corresponding indication. be injected.

In a study conducted in 1997 showed fluspirilene as the second most common cause of tardive dyskinesia after haloperidol. A few applications may be sufficient for triggering dyskinesias. Even so be warned before it is used to treat depression.