Gallopamil

  • (RS ) -5 - [(3,4 - dimethoxyphenethyl ) methylamino ] -2 - isopropyl- 2-( 3,4,5 - trimethoxyphenyl) pentanenitrile
  • (±)- methoxyverapamil
  • C28H40N2O5 ( gallopamil )
  • C28H40N2O5 · HCl (hydrochloride)

C08DA02

Yellow viscous oil ( gallopamil )

Calcium antagonist

  • 484.63 g · mol -1 ( gallopamil )
  • 521.10 g.mol -1 (hydrochloride)

240-245 ° C ( 0 to 26.6 Pa, gallopamil )

1.5402 (hydrochloride)

Hydrochloride

Template: Infobox chemical / molecular formula search available

Gallopamil is a drug from the group of nitriles. IUPAC name is the racemate (± ) -5 - [(3,4 - dimethoxyphenethyl ) methylamino ] -2 - isopropyl- 2-( 3,4,5 - trimethoxyphenyl) pentanenitrile.

Properties

It is a calcium antagonist and calcium channel blocker. This characteristic has the result that the Ca2 - ions can not diffuse as in the undisturbed state in the cells. A muscle contraction remains of why or relaxes, resulting in large blood vessels or the heart muscle itself is relaxed.

Use

Gallopamil is used in medicine for the treatment of cardiovascular diseases, particularly in diseases of the coronary vessels, such B.Angina pectoris, cardiac arrhythmias, or hypertension.

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Active ingredient British Journal of Clinical Pharmacology PubMed Central
360020
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