Gensler graduated from 1974 to 1978 to study at the Wharton School, University of Pennsylvania, he with a B.Sc. economics completed. In 1979 he was awarded the MBA. Then Gensler worked for the U.S. investment bank Goldman Sachs, before he began his political career.
Gensler was 1997-1999 Under-Secretary at the U.S. Treasury ( Assistant Secretary of the Treasury ); then he served until 2001 as Secretary of State ( Under Secretary of the Treasury ).
He was married to Francesca Danieli († 2006), with whom he has three daughters and lives near Baltimore.