Grape and raisin toxicity in dogs

A grape poisoning is poisoning by ingestion of grapes, which occurs only in some dogs. The responsible " grape toxin " has not been identified so far.

A grape poisoning can already at admission of 10 g of grapes per kg body mass (BM ) or less than 2.8 g raisins / kg body weight occur. Even the often expelled in harvested vineyards pomace can cause poisoning. However, grapes and related products are not generally toxic to dogs, there appears to be an individual predisposition. Symptoms of poisoning occur after a few to up to 24 hours. First, there is vomiting, later to Fressunlust, fatigue, abdominal pain and diarrhea. These symptoms can last for several days. When the intake of larger quantities may follow in the blood, renal failure with elevated calcium, urea, creatinine and phosphorus content. The mortality rate in affected dogs of up to 50 %. Histologically, affected animals show necrosis of the renal tubules.

A causal therapy is not known. Symptomatic can infusions, possibly also a peritoneal lavage be applied.