Guanidinium thiocyanate

  • Guanidine thiocyanate
  • Guanidiniumrhodanid

White, odorless solid

Fixed

1.29 g · cm -3

118 ° C

Decomposition: 115 ° C

Very well in water ( 1420 g · l-1 at 20 ° C)

Attention

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Guanidinium thiocyanate, and guanidine thiocyanate, the thiocyanate salt of the guanidine.

Use

Chaotrope as it is used for denaturation of proteins.

It is used in the inactivation of viruses. Guanidinium thiocyanate is used for the lysis of cells and virions and DNA and RNA isolation. A widely used method is the guanidinium - phenol -chloroform extraction.

CAS registry number Dangerous Substances Directive (67/548/EEC) Chaotropic agent Virus#Etymology RNA extraction Analytical Biochemistry
284355
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