Haplogroup H (mtDNA)

Haplogroup H is a human genetics haplogroup of the mitochondria.

The Cambridge Reference Sequence (CRS), the mitochondrial sequence, all other sequences are compared with that belongs to haplogroup H.

Haplogroup H is 40 % to 50 %, the most frequent mtDNA haplogroup in Europe. This haplogroup is also common in North Africa and the Middle East. This density decreases in the southeast of the continent to 20% in the Middle East and the Caucasus.

The nucleotide position 4336 is tRNA variant of haplogroup H in connection with the later onset of Alzheimer 's disease After FamilyTreeDNA.

In his popular book The Seven Daughters of Eve by Bryan Sykes is the original mother of this haplogroup Helena.


This phylogenetic tree of the subgroups of haplogroup H based on a paper by Mannis van Oven and Manfred Kayser and subsequent scientific research.

  • HV B H1 H1a H1a1
  • H1a2
  • H1c1
  • H1c2
  • H1c3
  • H1e1 H1e1a
  • H2a H2a1 H2a1a
  • H2a2a
  • H2a2b H2a2b1
  • H3a
  • H3b
  • H3c
  • H3d
  • H3e
  • H3f
  • H3G
  • H4a H4a1 H4a1a H4a1a1 H4a1a1a
  • H5 H5a H5a1
  • H5a2
  • H36a
  • H6A H6a1 H6a1a H6a1a1 H6a1a1a
  • H6a1b1
  • H6a1b2
  • H7A H7a1
  • H7b1
  • H9a
  • H10a H10a1
  • H11a H11a2
  • H13A H13a1 H13a1a H13a1a1 H13a1a1a
  • H13a2a H13a2a1
  • H13a2b1
  • H14a H14a1
  • H15A H15a1
  • H16a
  • H16b
  • H17a
  • H20A