Hegar's sign

The Hegar sign is a named after the gynecologist Alfred Hegar probable pregnancy sign. In the second and third month of pregnancy is the area of the isthmus uteri, which lies between uterine body (corpus uteri ) and the cervix ( cervix uteri ), softer and lighter compressible on palpation (palpation ). The cause is a changing composition of the connective tissue during pregnancy due to the activation of proteases. This leads to an increased storage of water and a reorganization and relative reduction of collagen fibrils.