Heinrich Reichert

Heinrich Reichert ( born September 25, 1949 in Braunau am Inn ) is a Swiss development and neurobiologist at the Biozentrum, University of Basel.

Life

Heinrich Reichert studied physics, chemistry and biology at the University of Karlsruhe. After receiving his doctorate in 1979 at the University of Freiburg i Breisgau, he conducted research in the Department of Genetics three years at Stanford University, California. 1982 Heinrich Reichert went to the Zoological Institute of the University of Basel. Between 1986 and 1991, followed by a teaching and research time at the University of Geneva, before Heinrich Reichert returned again to the University of Basel. Here he worked as a professor at the Zoological Institute until 2006 and then went to the Biozentrum, University of Basel, where he teaches and conducts research since then.

Work

Heinrich Reichert examines the example of the fruit fly Drosophila, the importance of neural stem cells in the development of the brain. He discovered a molecular production program, after running the development of these stem cells in the brain. A similar evolutionary conserved development program is also involved in the development of brains in vertebrates. If the course of the program disrupted by targeted gene mutation that produce stem cells uncontrollably fail programmed cells that divide uncontrollably. The consequence is the formation of deadly brain tumors. As such genetic errors in the development of neural stem cells come about, Heinrich Reichert explored in detail. Its aim is to search for new strategies to prevent the formation of such brain tumors.

Awards

  • 2000 Neurex founding member and vice president
  • 2005 Scientific Member of the European Doctoral School, Strasbourg

List of publications

  • Spatz HC, Emanns A, Reichert H ( 1974) Associative learning of Drosophila melanogaster. Nature ( Lond ) 248:359-361
  • Reichert H, Wine JJ (1982 ) Neural mechanisms for serial order in a stereotyped behavior sequence. Nature ( Lond ) 196:86-87
  • Robertson RM, Pearson KG, Reichert H ( 1982) Flight interneurons in the locust and the origin of insect wings. Science 217:177-179
  • Reichert H, Rowell CHF, Griss C ( 1985) Course correction circuitry trans lates feature detection into behavioral action in locusts. Nature ( Lond ) 315:142-144
  • Hirth F, Therianos S, Loop T, Gehring WJ, Reichert H, Tokunaga K - Furukubo (1995 ) Developmental defects in brain segmentation Caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila. neuron 15:769-778
  • Leuzinger S, Hirth F, Gehrlich D, Acampora D, Simeone A, Gehring WJ, Finkelstein R, Furukubo - Tokunaga K, Reichert H ( 1998) Equivalence of the fly gene and the human OTX orthodenticle genes in embryonic brain development of Drosophila. Development 125:1703-1710
  • Hirth F, chamber Meier L, Free E, ​​Walldorf U, Noll M, Reichert H ( 2003) On urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila. Development 130:2365-2373
  • Bello B, Izergina N, Caussinus E, Reichert H ( 2008) Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development. Neural Development 2008, 3:5
  • Boyan GS, Reichert H ( 2011) Mechanisms for complexity in the brain: generating the insect central complex. Trends Neurosci 34:247-257
  • Berger C, Harz H, Burkhard T, Steinmann J, van der Horst S, Laurenson AS, Novatchkova M, Reichert H, Knoblich J (2012 ) Transcriptome analysis of Drosophila neural stem cells Reveals a transcriptional network for self -renewal. Cell Reports 2:1-12
Developmental biology
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