Hepatocyte

Called hepatocytes, liver cells or hepatocytes also, about 20 to 30 micrometers are large cells, occupying about 80 percent of liver volume. They originate from the endoderm of the intestinal system.

Cell organelles

The hepatocytes are metabolically very active and contain numerous cell organelles:

• Diploid and polyploid nuclei

• Mitochondria

• Lysosomes

• Peroxisomes

• Endoplasmic reticulum

• Individual lipid droplets

• Glykogenfelder (the amount of glycogen is dependent on diet and subject to daily fluctuations )

• Highly developed Golgi apparatus

• Secretory vesicles

• Well-developed cytoskeleton

Construction

The hepatocyte, like all epithelial cells, a polarized construction and operation. They possess a basolateral ( sinusoidal ) and apical ( canalicular ) membrane, but no basal lamina.

The narrow apical Gallepol bears numerous microvilli and secretes bile. The broad basolateral Blutpol also bordered by microvilli to a Sinusoid and is responsible for the exchange of substances between blood and hepatocyte.

Function

The hepatocytes are involved in many metabolic processes and have the following important functions:

• Detoxification with many conversion reactions ( urea cycle, class - I and class - II - transformation reactions )

• Synthesis of fatty acids

• Synthesis of bile acids

• Protein synthesis (eg, albumin, lipoproteins, coagulation factors, cholinesterases )

• Liver
• Cell type
• Histology of the digestive system