Hexachlorophene

• 2,2 ' -methylenebis ( 3,4,6 -trichlorophenol )
• Nabac

D08AE01

Light brown solid

Fixed

166-167 ° C

• Insoluble in water
• Soluble in ethanol, diethyl ether, acetone, chloroform, olive oil, polyethylene glycols, and dilute aqueous alkali solution

Risk

56 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Hexachlorophene is a chlorinated bisphenol A and hence a chlorinated hydrocarbon which is used as a disinfectant.

Representation

Hexachlorophene is prepared by the condensation of 2,4,5 -trichlorophenol with formaldehyde in the presence of concentrated sulfuric acid.

Effect

Hexachlorophene is highly bactericidal against gram- positive bacteria. The growth of Staphylococcus aureus on agar or hindered by hexachlorophene in a dilution of 1:8.000.000. Hexachlorophene has a skin, eyes and mucous membranes, neurotoxic and embryotoxic in higher concentrations. In laboratory animals, damage to the white matter of the brain and the spinal cord were observed. In large amounts, taken orally, hexachlorophene leads to loss of appetite, diarrhea, and paralysis.

Use

Is hexachlorophene as a disinfectant, drug use ( for Trichophyten and Trematodenbehandlung, acne and hemorrhoids as well as in the livestock sector ) and as a pesticide. It also serves as a microbicide in cosmetics (since 1985 in the Federal Republic of Germany banned ), detergents and cleaning products and as an additive to textiles and plastics. These applications come in recycling processes (paper, toilet paper, ... ).

Ban

Since January 1, 1990 hexachlorophenhaltige substances in Austria may no longer be placed on the market. In Germany the use in cosmetics has been banned since 1985.