2,5 - dihydroxyphenylacetic
152-154 ° C ( monohydrate)
Template: Infobox chemical / molecular formula search available
Homogentisic acid is an intermediate in the degradation of the amino acids phenylalanine and tyrosine, and is at physiological pH values as an anion at the moment ( homogentisate ). It is used by the enzyme homogentisate dioxygenase ( EC 188.8.131.52 ) is converted into 4- Maleylacetessigsäure:
In consequence, result acetoacetic acid and fumaric acid, which can be fed into the citric acid cycle.
In the metabolic disease alkaptonuria lack the enzyme or is not available to a sufficient extent. " Alkapton " is the oxidized form of the black-brown Homogentisats.