HPU is the abbreviation for:

  • Hämopyrrollaktamurie, a manifestation of the condition porphyrinuria
  • Hawaii Pacific University in Honolulu and Kaneohe, Hawaii, USA
  • Howard Payne University in Brownwood, Texas, United States
  • High Point University in High Point, North Carolina, United States
  • Hydrolysis the material polyurethane, also known as thermoplastic polyurethane, see Polyurethanes

HPU as distinguishing signs on license plate:

  • Poland: Police indicator for the Greater Poland Voivodeship
  • Disambiguation
  • Abbreviation