Humulone

• α - Lupulinsäure
• α -humulone
• (6R) -3,5,6 -trihydroxy- 4 ,6-bis (3-methyl -2-butenyl ) -2 - (3- methyl-1- oxobutyl ) -2,4- cyclohexadiene- 1-one ( IUPAC )

• 23510-81-8
• 26472-41-3 [(R) -humulone ]

Fixed

66 ° C.

Template: Infobox chemical / molecular formula search available

Humulone (also α - Lupulinsäure ) is a bacteriostatic bitter substance from the resin of ripe hops Humulus lupulus. its rearrangement products formed by heating (especially cis -and trans- isohumulone ) give the beer its characteristic bitter taste, he is counted among the hop bitter compounds.

Structurally humulone is a hydroxy- phloroglucinol with three isoprenoid side chains. An anti-inflammatory action of humulone was detected as a suppression of the transcription of the cyclooxygenase-2 (COX-2 ) associated with the gene, whereby the formation of prostaglandins is inhibited.