Interphase

Interphase denotes a phase of the cell cycle of eukaryotic cells. Interphase is the period between the last and the next nuclear division (mitosis ). Interphase is the longest phase of the cell cycle and can in actively dividing cells account for up to 90 % of the total cell cycle. During interphase of the cell nucleus is consistently available.

The interphase can be divided into 3 phases:

• In the G1 phase (G of engl. "Gap " = gap), which connects directly to cell division, is essentially cell growth and formation of organelles. Also protein and RNA synthesis. Each chromosome consists of a chromatid. This is the phase in which the cell reaches its typical nuclear-cytoplasmic ratio and performs its specific function until a certain nuclear-cytoplasmic ratio is exceeded.

• In the following S ( synthesis ) phase replication of chromatids or DNA takes place. Afterwards, each chromosome consists of two chromatids. In many cells and the centrosome is doubled in this phase.

• Further growth in the G2 phase finally takes place (there is also again protein synthesis and RNA synthesis takes ). Thus, the cell prepares for the next mitosis, and also checks whether the replication is complete and without error so ever can occur cell division.

Thereafter, the M- phase, followed by mitosis.

Under special circumstances, the cell ( the so-called resting phase ) passes into the G0 phase of the G1 phase. The transition to a G0 phase is often reversible, Stem cells can remain a long time in this phase. If, however, a specialization in terms of enduring differentiation, no further cell division takes place more in some cell types and the cell remains irreversible in the G0 phase. One example is nerve cells.

• Biological process
• Cell cycle