Iron(II) fumarate

  • Iron (II) - (E)- but-2- endioat (IUPAC)
  • Feostat

B03AA02

Red - brown powder

Fixed

1.44 g · cm -3

279-281 ° C

3850 mg · kg -1 ( LD50, rat, oral)

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Iron (II) fumarate is a divalent iron salt of fumaric acid is used in the oral treatment of iron deficiency anemia substitution.

Biological Significance

Iron is absorbed only in its divalent form in the intestine. The intake of the drug should be taken on an empty stomach, because here is the iron absorption is greatest. However, gastrointestinal complaints can occur in susceptible patients. Also, antacids may inhibit iron absorption. In this case, a division of the dose in divided doses is recommended. Concomitant intake of vitamin C-containing meals may improve tolerability.

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Dangerous Substances Directive (67/548/EEC)
300337
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