Ivan Đikić

Ivan Đikić (born 1966 in Zagreb) is a Croatian biochemist and molecular biologist.

Life

Ivan Đikić graduated in 1991 his studies in medicine at the University of Zagreb in a record time of four and a half years with an excellent exam from. He received his doctorate in New York with Joseph Schlessinger and thereafter worked in research projects in Israel and Sweden, as well as in Germany, where he (as of 2012) at the University Hospital in Frankfurt am Main is a professor of biochemistry today.

Work

Đikićs focus is the ubiquitin research. As head of the Biochemistry team at the Goethe Institute, he was instrumental in the discovery of the role of ubiquitin as a signal molecule of the cell, for example in the regulation of DNA either repairing, membrane transport (receptor -mediated endocytosis ), in inflammation and in protein degradation with proteasomes. His group identified several ubiquitin - binding sites ( ubiquitin binding domains) and he developed methods to the study of ubiquitin chains in vivo with specific ubiquitin sensors. Research has applications in the elucidation of molecular mechanisms of carcinogenesis.

2008 published Đikić and Koraljka Husak at the University of Frankfurt, where he has worked since 2002, their discovery of clues that have an important role in the development of tumors and diseases of the nervous system.

Awards and Memberships (Selection)

Croats Informationsdienst Wissenschaft
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