Ivar Karl Ugi

Ivar Karl Ugi ( born September 5, 1930 in Kuressaare on the island of Saaremaa in Estonia, † September 29, 2005 in Munich) was a German - Estonian chemist who made major contributions to organic chemistry delivered, especially to the multi-component reactions. Such a reaction is named after him Ugi reaction.

Life

Ivar Ugi. grew up in Estonia and came to Germany in 1941, where he studied chemistry at the University of Tübingen began in 1949. From 1951 to 1954 he studied until the conclusion as Dr. rer. nat. at the Ludwig- Maximilians- University of Munich, his doctor father was Rolf Huisgen. Ugi habilitated in 1960 in Munich. Two years later, he worked with some success at Bayer AG in Leverkusen ( 1962-1968 ) and there rose the Commission for Basic Research to the Director of the Central Research and chairman on, but then turned back to academic research.

So Ugi spent three years at the University of Southern California in Los Angeles as Professor of Chemistry (1968 to 1971), after which he the Chair of Organic Chemistry I by Friedrich Weygand took over at the Technical University of Munich. Ugi was Chairman of the first International Conference on Computers in Chemical Research and Education ( International Conference on Computers in Chemical Research and Education, ICCCRE ) in Garmisch -Partenkirchen in 1985. In October 2000, he joined as a co-organizer of the first conference for multi -component reaction ( First International Conference on Multicomponent Reactions, MCR 2000) on. In 1987, Ugi was admitted to the Royal Swedish Academy of Sciences, in 1990 in the Estonian Academy of Sciences in 1994 and an honorary member of the New York Academy of Sciences. Even as he remained Emeritus of the University of Munich from 1999 until his death in 2005 connected.

Research

With over 400 publications Ugi was an extremely prolific researcher, with special work on the Ugi reaction protrude. In this Multikompenentenreaktion, the so-called one-pot reaction of a ketone or aldehyde, an amine, an isocyanide and a carboxylic acid to the bis- amides, which can be used for a variety of synthetic form. Sometimes the expansion of the Ugi reaction in the art is also called Ugi chemistry. The seminal work on the multi -component reaction served as a starting point for further work. So Ben cunning and Jürgen Martens developed ( University of Oldenburg ) related variants of the Ugi reaction. In addition, he explored the Arylpentazole, chemical libraries, chiral ferrocenes, reaction mechanisms and preparation of organic phosphorus compounds, esters of Fluorocarbonsäuren, kinetics of reactions, stereochemistry of mathematical theories and mathematical models of chemistry with the help of computational chemistry. To this end, developed Ugi with the friend, the mathematician James Dugundji the idea of an algebraic chemistry, chemical starting materials used in a reaction such as numbers in an algebraic equation.

Awards

For the discovery of his four-component reaction and the development of mathematical models for the chemical Ugi in 1964 awarded the Chemistry Prize of the Academy of Sciences in Göttingen. In 1988 he was awarded the Philip Morris Research Prize Challenge and Future Prize 1992, the Emil Fischer Medal of the German Chemical Society for the advancement of computational chemistry and multicomponent reactions. The first Ugi Dugundji Medal was awarded to him in 1995 for the seminal work on the application of mathematics in chemistry from the Second International Symposium on Knowledge Acquisition in Auburn (Alabama, USA). In October 1999 he was awarded for the Development of peptide chemistry research the Max Bergmann Medal.

Writings

  • The α -addition of immonium ion and anion to Isonitriles Accompanied by Secondary Reactions. In: Angew. Chem Int. Ed. Engl 1 (1 ), 1962, pp. 8-21.

Swell

  • Press release on the 75th birthday of Ivar Ugi
  • CV TUM (English)
  • Peter Lemmen, Eric Fontain, Johannes Bauer: Ivar K. Ugi ( 1930-2005 ). Multicomponent Reactions, Computer and Phosphorus Chemistry. In: Angewandte Chemie International Edition. 45 (2 ), 2005, pp. 193
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