Even before graduation the son of a factory left the school to devote himself entirely to acting. His debut as a theater actor he was 19 years old at the Munich Chamber games. First experience as a cabaret artist he gained in the student cabaret " The firecrackers ". Three years he was in Düsseldorf Kom (m) ödchen active. From 1976 to 1991, Jochen Busse was part of the ensemble and writing team of the Munich laughing and shooting society.
From the late 1960s, took over buses also roles in films and television productions. Here he was, as initially mostly used in the three- splitter 11 clock 20 as the ice-cold villain. In 1972 he won the role of detective wizard Siebenlist in the ZDF detective series Homicide, where he encouraged by director Kurt Wilhelm, was able to show his comedic talent, for the first time. In 1978 he started with the WDR series media clinic his own show, and later he was the focal point of the sketch series only for buses. In these episodes, the multi-talented buses showed itself mainly as a comedian. In 1994 he played with Gerd Baltus and Karsten bacon in the series 3 man in bed the patient Gisbert. From 1996 to 2005 he hosted the broadcast of RTL and produced by Rudi Carrell Friday evening show 7 days 7 heads. He also celebrated in February 1997 as a senior administrator Hagen Krause in the RTL series The Office in over 70 episodes a success. In 2000, he staged at the Schiller Theater in Wuppertal Heinrich von Kleist's The Broken Jug. In 2005 he played the aliens YOK in the comedy series Not of this world. In April 2006, he was host of the comedy chat show The hot porridge on Sat.1, the actor, the roles of politicians and celebrities play. In addition to his acting career, he also worked as a screenwriter. In 2007, he moderated in the NDR broadcast laughter fun. Since late 2007, he toured with Henning Venske and the program meets veteran legend by the German-speaking countries. On September 22, 2009, both making their debut with the stage program inventory. 2014 Jochen Busse first appeared in his long career with a solo program before his audience. In How I now come on it there? comes from the comedian without scenery, without music and without costumes.
Jochen Busse supported in 2012 as honorary reciter the project " German Winterreise" the author Stefan Weiller. In it, attention is drawn in particular to the situation of the homeless since 2009 urban based, in collaboration with institutions such as the Social Service Agency at fundraisers in a song and text cycle.
1978 bus first marriage was with a film editor. In his second marriage he was married from 1994 to 2000 with Sabine Kersten, from this marriage comes a son. From 2002 to 2006 he was associated with the filmmaker Bea summer. In fourth marriage, he is married to Constanze Volkner since November 5, 2007, the four year old twins brought into the marriage.