Kopexil

• 2,3-dihydro -3-hydroxy -2 -imino -4- pyrimidinamine
• 2,4 - Diamino - 3-oxide
• Aminexil
• Diaminopyrimidine OXIDE (INCI)

White, odorless crystals

210-218 ° C

Slightly soluble in water

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Kopexil (brand name Aminexil ) is a synthetic chemical compound that is one of the pyrimidine and guanidine derivatives. Kopexil is the parent compound of minoxidil. Kopexil was originally used to treat high blood pressure as a side effect showed that an increased body was thrown.

Chemical structure

Chemically counts Kopexil to the N- oxide, a substance group on the nitrogen atom of a tertiary amine as the fourth residue has an oxo function, so it is oxidized. As the nitrogen atom of the amidine Kopexils simultaneously belongs to a sub- structure, two tautomeric structures of the compound can be formulated.

Mechanism of Action

The exact mechanism of action of Kopexil are to this day still only guesses. Furthermore, the effectiveness of hair loss is not detected.

Use in hair cosmetics

Kopexil locally - usually in conjunction with Minoxidil and Retinol - used to counteract hair loss due to premature exhaustion of the hair root, thus enabling a better anchoring of the hair in the scalp. The concentration of Kopexil this amounts to eg 1.5 %.