Latrotoxin

Alpha - latrotoxin is a neurotoxin and major component of the Real of spiders of the genus widows ( Latrodectus ) produced in the venom glands poison mixture.

Operation

Alpha - latrotoxin is a relatively large molecular weight toxin that exerts its effects on the peripheral nervous system. It works by opening additional calcium channels in the presynaptic nerve cell to the structure of the toxin itself is instrumental in probable and which are permeable particularly for calcium ions. By calcium ion influx into the cell transmitter constantly be discharged, so a persistent signal. It comes to cramps. Leading to death the poison when the cramps affected the respiratory system and cause suffocation ( due to respiratory failure or edema).

  • Membrane channel
  • Animal poison
  • Neurotoxin
Neurotransmitter
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