Leukopenia

As leukopenia, leukopenia completely, ( from Ancient Greek λευκός leukos "white"; ancient Greek κύτος kytos " hollow ", " vessel ", "shell", and ancient Greek πενία PENIA "poverty", "deficiency" ) is a lack of leukocytes ( white blood cells ) referred to in the blood. This means that there has been a reduction in the white blood cell count to below 4000 per microliter of blood. In most cases, there is a reduction of neutrophils before ( neutrophilic granulocytopenia, and neutropenia). A decrease in lymphocytes ( lymphopenia ), however, often leads to reduced total white. The opposite of leukopenia is the leukocytosis.

To a neutrophilic granulocytopenia example, it may in the context of an infectious disease, such as typhoid fever, chemotherapy or blood-related diseases occur (eg, sepsis, aplastic anemia, leukemia, myelodysplastic syndrome, allergy). With greatly reduced white blood cell counts, the patient an increased risk of infection is exposed.

A replacement of granulocytes by granulocyte is possible and not very effective in only a few treatment centers, as the transfused granulocytes only have a very short life. The use of granulocyte transfusions has not found general acceptance. It is possible to increase the leukocyte count drug by administration of hematopoietic growth factors such as G -CSF. Drugs, for example, lenograstim ( Granocyte ), Filgrastim ( Neupogen ) and pegfilgrastim ( Neulasta ).

Under certain circumstances, a reverse isolation is required.

  • Pathophysiology
  • Blood count
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