The " reliable left-back " played in the 1900s and 1910s for Quick Den Haag and was a member of the champion team of 1908. In addition, he played from 1907 to 1911 twelve caps for the Dutch national team, four of them as a team leader. In 1908 he was part of the team that won the bronze medal in London at the Olympics.
Otten was a PhD doctor and professor of medicine. He discovered a vaccine against the bubonic plague; In 1934 he tried for the first time live vaccination on Java in the former Dutch East Indies, where he worked in Bandung Institut Pasteur. During the Second World War he was in Japanese prisoner of war.