Lysidine (nucleoside)

  • K2C ( short code )
  • 2-Amino-6-[4-amino-1-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-ylidenamino]-hexansäure
  • 4-amino- 2-( N ( 6) - lysino )-1- ribofuranosylpyrimidin

Fixed

Template: Infobox chemical / molecular formula search available

Lysidine ( K2C ) is a rare nucleoside and occurs in the tRNA. It consists of the β -D - ribofuranose (sugar) and a derivative of cytosine, wherein the carbonyl group has been replaced by the amino acid lysine. This substitution pattern is similar to that of the nucleoside Agmatidin.

Properties

Bacteria decode the isoleucine codon AUA with a tRNA, was changed at the third position of the anticodon ( position 34 ) of cytidine on lysidine. Cytidine mates usually with guanosine, lysidine mates, however, only with adenosine. Uridine is not installed at this point, although it is the usual source for adenosine; however, it may also form a " wobble base pair " with guanosine. Therefore lysidine ensures its uniqueness in the base pairing better reliability of the translation.

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