Meglumine

  • Meglumine
  • Methylglucamine
  • 1 -deoxy- 1- methylaminosorbit
  • NMDG
  • NMG

White, odorless solid

Fixed

128-131 ° C

210 ° C ( decomposition)

Slightly soluble in water: 1000 g · l-1 (25 ° C)

> 5000 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

N-methyl -D-glucamine ( NMDG Abbr or NMG also meglumine ) is a chemical compound which is derived from D-glucose. Instead of the aldehyde oxygen of the glucose it carries a methylamino group. The amine reacts basic, the nitrogen is incorporated, a proton that is in the position. As a result, N-methyl -D-glucamine in an aqueous solution charged to the positive portion.

In electrophysiology of N-methyl -D-glucamine is used as a substitute for sodium ions (Na ). NMDG characterized by an osmotic activity similar to that of sodium ions. Cell membranes are impermeable to NMDG. Also in culture media NMDG is used as a sodium substitute, such as when the cultured cells are sensitive to Na ions.

CAS registry number PubChem Base (chemistry)
9110
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