Meropenem

Latin: Meropenemum

  • 96036-03-2 ( meropenem )
  • 119478-56-7 ( meropenem trihydrate )

J01DH02

White to slightly yellow crystalline powder ( meropenem trihydrate )

β -lactam antibiotics, carbapenem

Inhibition of cell wall synthesis

Slightly soluble in water, very slightly soluble in dilute ethanol, practically insoluble in acetone and diethyl ether (trihydrate )

2650 mg · kg -1 ( LD50, mouse, i.v.)

Template: Infobox chemical / molecular formula search available

Meropenem is a drug which is belongs to the group of carbapenems and marketed by AstraZeneca.

Pharmacology

See carbapenems, unlike imipenem, meropenem is stable against dehydropeptidase I.

Spectrum of activity

The spectrum of activity is greater in the range of Gram-negative bacteria compared to imipenem.

Side effects

The side effects are similar to that of the penicillins and cephalosporins. It can, however, also epileptic seizures.

Trade names

Meropenem (D, CH), Optinem (A)

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System DrugBank Active ingredient
565016
de