Mesenchyme

Mesenchyme (Greek, the middle Infused ') together with the gelatinous connective tissue embryonic connective tissue. From the mesenchyme develops:

• Loose, tight and reticular connective tissue
• Bone and cartilage
• Smooth muscle and cardiac muscle
• Kidney and adrenal cortex
• Blood -forming system, blood and lymphatic vessels

Construction

Mesenchymal cells is composed of star-branched, are referred to as mesenchymal stem cells, mesenchymal stromal cells or mesenchymal cells. You are about cytoplasmic together in mechanical and communicative connection. Mesenchymal stem cells have a high rate of division ( mitosis ) and are referred to as multipotent because they can differentiate into many different tissue.

The intercellular substance consists essentially of a viscous, hyaluronic acid- containing liquid. It contains only from the eighth week of development collagen fibrils, but no fibers. So that differs significantly from mesenchyme -differentiated connective tissue that forms a generally fibrous intercellular substance that makes the properties of the fabric.

Histogenesis

Mesenchyme occurs from the third week of development in the human embryo. It is caused by detachment of cells from the cotyledons of the embryo, especially from the mesoderm, but also from certain portions of the ectoderm ( neural crest ) and endoderm ( prechordal plate ).

Diseases

Tumors arising from the mesenchyme called Mesenchymome. Malignant tumors of mesenchymal origin tissues are called sarcomas.

Therapy Research

In the context of stem cell research will examine the extent to which mesenchymal cells can be used to treat degenerative diseased organs of mesenchymal origin. See also: Adult stem cells and therapeutic options